Acute Pharmacological DVT Prophylaxis after Spinal Cord Injury

Pharmacological Therapy for Acute Spinal Cord Injury.

• Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI) is not recommended. Clinicians considering MP therapy should bear in mind that the drug is not Food and Drug Administration (FDA) approved for this application. There is no Class I or Class II medical evidence supporting the clinical benefit of MP in the treatment of acute SCI. Scattered reports of C...

Pharmacological management of acute spinal cord injury.

Acute Spinal Cord Injury: Pharmacological Interventions

Researchers are wary of giving people false hopes that a magic bullet for curing spinal cord injury is just around the corner. However, with accelerating progress in scientific research, there is renewed vitality and growing optimism that, with continued effort, the problems of spinal cord injury will be overcome. Although many years of intensive study have contributed to the development of the...

P7: Valproic Acid Mediated Neuroprotection and Neurogenesis after Acute Spinal Cord Injury

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Cellular and Molecular Mechanisms Involved in Neuroinflammation after Acute Traumatic Spinal Cord Injury

Introduction: Spinal cord injury (SCI) following traumatic events is associated with the limited therapeutic options and sever complications, which can be partly due to inflammatory response. Therefore, this study aims to explore the role of inflammation in spinal cord injury. The findings showed that the pathological conditions of nervous system lead to activation of microglia, astrocyte, neut...